Palo Alto Networks Deepens AI Security Capabilities Through Expanded Cloud Alliance

As organizations accelerate adoption of agentic AI and cloud-native architectures, security leaders are under mounting pressure to protect increasingly autonomous, data-intensive systems. Addressing this challenge, Palo Alto Networks has expanded its strategic collaboration with a leading hyperscale cloud provider to deliver a security-first foundation for AI-driven enterprises.

The expanded alliance brings together advanced cloud infrastructure and AI services with Prisma® AIRS™, Palo Alto Networks’ comprehensive AI security platform, enabling enterprises to build, deploy, and operate AI applications with security embedded by design rather than added as an afterthought.

Findings from Palo Alto Networks’ State of Cloud Report (December 2025) underscore the urgency: nearly all surveyed organizations reported at least one security incident targeting their AI infrastructure in the past year, as cloud environments rapidly scale to support new AI workloads. These trends highlight the growing attack surface created by AI models, autonomous agents, and complex hybrid multicloud deployments.

The strengthened partnership is designed to confront these risks by integrating security across every layer of the AI lifecycle—from development and deployment to runtime and access—while supporting faster innovation and operational resilience.

Key outcomes of the expanded collaboration include:

Comprehensive AI security across the full lifecycle

Organizations can now secure active AI workloads, data pipelines, and autonomous agents running in cloud environments using Prisma AIRS. The platform provides end-to-end protection, including AI posture management for visibility, runtime security for real-time threat prevention, safeguards for AI agents, proactive red-teaming capabilities, and model-level vulnerability scanning. By extending protection to developer workflows and toolchains, enterprises gain a hardened foundation for building next-generation AI applications.

Next-generation software-based firewalling for cloud environments

Palo Alto Networks’ VM-Series firewalls deliver advanced threat prevention and deep traffic inspection in software form, tailored for modern cloud and virtualized infrastructures. Enhanced cloud integrations allow enterprises to apply consistent security policies while scaling AI workloads and accelerating cloud adoption without compromising protection.

AI-powered secure access and networking

Through its Prisma SASE platform, Palo Alto Networks strengthens secure connectivity for remote users, branch locations, and mobile workforces accessing AI and cloud applications. By leveraging high-performance global networking infrastructure, organizations benefit from improved user experience, optimized application access, and unified security enforcement across multi-cloud and hybrid environments.

Together, these capabilities enable enterprises to confidently scale AI initiatives, protect sensitive intellectual property and data, and reduce operational risk—while keeping security aligned with the speed and complexity of modern AI-driven business.